Please follow the instructions on pages 9 – 11 and C on page 12.Under the Criteria – Evaluation of Research , please apply the PICO question “In patients with chronic pain, what is the effectiveness

 Please follow the instructions on pages 9 – 11 and C on page 12.Under the Criteria – Evaluation of Research , please apply the PICO question “In patients with chronic pain, what is the effectiveness of alternative medicine and non-opioid use compared to exclusive opioid use in regards to pain control, quality of life, and overall functioning?”Paper CommentsThe reference for the paper that will be uploaded fromhttp://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.820.9786&rep=rep1&type=pdf